Dreamy Garlic Butter Shrimp Scampi Lasagna

As seen in Satisfying Entrées for Every Table.

Bake it all together: loads of gooey mozzarella and Parm, juicy shrimp, and a lemony, creamy garlic sauce sandwiched between lasagna noodles. The cheese turns golden on top while parsley and fresh ground pepper make everything taste even brighter. Sauté shrimp for just a minute or two, whisk up a buttery sauce, then build your stacks of noodles and cheese. Bake until bubbly with crisp edges. You can even make it ahead and swap in veggies if you want, or go lighter on the cream. Scoop it onto plates, add a little more parsley, and dig in!

Barbara Chef
Created By Sasha
Last updated on Wed, 02 Jul 2025 18:22:01 GMT
Shrimp and cheese layered in a savory dish. Save Pin
Shrimp and cheese layered in a savory dish. | foodthingle.com

Imagine tucking into layers of tender noodles hugged with a buttery garlicky sauce and loaded with plump shrimp all finished with melty golden cheese This cozy twist is like your favorite seafood dinner meets comfort food and it’s just as good at the table with friends as it would be at your favorite spot but way more relaxing

The first time I whipped this up, my husband couldn’t even finish his plate before reaching for more It’s now a regular—any time I serve it the room goes quiet except for happy sighs and busy forks

Luscious Ingredients

  • Lemon juice: Squeeze fresh lemon to brighten your sauce big time
  • Salt and pepper to taste: These lift every other flavor so don’t forget them Taste as you go
  • Chopped fresh parsley: A handful of vibrant green parsley adds a fresh finish
  • Shredded mozzarella cheese: Pick whole milk mozzarella for the best melt and irresistible cheesy topping
  • Grated Parmesan cheese: Savory and nutty—use the good stuff for rich flavor
  • Milk: Go with whole milk if you can but any milk works to make the sauce nice and creamy
  • All-purpose flour: Helps turn your sauce thick and silky
  • Butter: Don’t skimp—real butter makes the garlic sauce shine
  • Garlic: Fresh cloves bring bold flavor to both shrimp and sauce
  • Large shrimp: Look for peeled and deveined. Either fresh or frozen is fine just pat dry
  • Lasagna noodles: Classic or no-boil noodles both do the trick to hold all those flavors

Step-by-Step Directions

Bake and Finish:
Pop your lasagna into a hot oven at three seventy five degrees for twenty five minutes covered with foil Remove the foil for another ten minutes till the top is bubbly and golden Let the pan cool a bit before you cut in Scatter that fresh parsley right before serving
Layer Everything Up:
Drizzle a bit of sauce onto the base of your casserole dish Line with noodles Add more sauce and a generous amount of shrimp Next comes mozzarella cheese layer Start again with noodles and keep building. Save plenty of mozzarella to finish the top
Finish the Cream Sauce:
Once your sauce thickens after about five minutes off the heat Mix in your grated Parmesan Stir well till smooth. Test if it’s salty enough and add a good squeeze of lemon
Thicken the Sauce:
Using the same skillet toss in some butter again Medium heat Garlic goes in for a quick sizzle Sprinkle in flour and whisk so there are no dry bits Let it bubble just for a minute
Cook the Shrimp:
Slide the shrimp into the garlicky butter Let them cook about two to three minutes each side Flip once and pull them out when they curl and turn pink Don’t leave them; set aside so they stay juicy
Sauté Garlic in Butter:
Melt butter in a wide pan over medium Add your chopped garlic Cook gently for a couple minutes till it smells amazing Keep stirring so nothing burns
Get the Noodles Ready:
Start by boiling your noodles in salty water till they’re just tender Not too soft since they’ll bake a bit more Drain and lay them flat on a towel so they won’t clump up
A plate stacked with cheesy shrimp and golden crust. Save Pin
A plate stacked with cheesy shrimp and golden crust. | foodthingle.com

I can’t get enough of that hit of lemon brightening the buttery sauce My favorite story? Watching friends lean across the table to soak up the garlicky aroma the first time I served it on New Year’s Eve

Tips for Keeping It Fresh

Keep leftover slices in an airtight container in the fridge for up to three days Rewarm single servings in the microwave with a splash of water so they don’t dry out You can freeze extras tightly wrapped for two months Let them defrost overnight in the fridge then pop in the oven till hot

Easy Ingredient Swaps

No fresh shrimp handy? Frozen works just dry it well before cooking Want to save cash? Use part white fish or even mock crab for similar texture Dairy free? Grab your favorite plant butter and non-dairy cheese and you’re all set

A plate stacked with cheesy shrimp and golden crust. Save Pin
A plate stacked with cheesy shrimp and golden crust. | foodthingle.com

How to Serve

Pair with a crisp green salad and lemony dressing to lighten each bite Toast up a loaf of crusty bread to scoop up every drop of sauce Hosting company? Top each plate with more fresh herbs and a sunny lemon wedge

How This Dish Connects

This one brings together classic Italian pasta tradition with the bold flavors of Italian American shrimp scampi You get comforting layers of baked pasta with the zesty savory punch of garlic seafood and lemon—sort of the best of both worlds

Common Recipe Questions

→ Could I use shrimp that's already cooked?

Stick with raw shrimp if you can, since baking can make pre-cooked shrimp tough and chewy. If you only have cooked shrimp, just toss them in while you're building the layers and skip cooking them beforehand.

→ How do I keep lasagna from turning out soupy?

After boiling, drain noodles really well. Make sure your sauce is on the thicker side before layering. Also, don’t splash a ton of sauce in the first layers, or you’ll end up with too much liquid at the bottom.

→ Can I swap out the cheeses?

Totally. You could try swapping in fontina or Gruyère for mozzarella, or use Pecorino Romano if you want a different taste than Parmesan.

→ What’s good to eat with this?

A crisp green salad, roasted veggies, or even some garlicky bread go perfectly alongside. They cut all that cheesy, buttery goodness and round out the meal.

→ Can I prep this whole thing earlier?

You bet. Put it all together the night before, wrap it up, then chill in the fridge. Just remember to add a little extra oven time when you bake it straight from cold.

→ How can I warm up leftovers?

Cover with foil and pop into a 350°F oven till it’s steaming, or heat single servings in the microwave until hot all the way through.

Shrimp Garlic Butter Lasagna

Melted cheese, shrimp, and dreamy garlic butter all stacked for the ultimate feel-good meal.

Preparation Time
30 Minutes
Cooking Time
35 Minutes
Overall Time
65 Minutes
Created By: Sasha

Recipe Type: Main Dishes

Skill Level: Moderate

Regional Style: Italian-American

Output: 8 Number of Servings (1 big pan lasagna)

Special Diets: ~

What You'll Need

→ Lasagna

01 Salt and a few cranks of black pepper as you like
02 Some fresh parsley, chopped (about 1/4 cup)
03 1 cup of mozzarella, shredded up
04 1 cup parmesan, grated fine
05 2 cups whole milk
06 1/4 cup all-purpose flour
07 Half a cup of unsalted butter
08 4 garlic cloves, smashed up
09 1 pound shrimp (get them big, peeled, and ready)
10 A box of lasagna noodles

→ Garlic Butter Sauce

11 Give or take 1 tablespoon lemon juice
12 Salt and pepper, add however much you want
13 Some chopped parsley, about a fourth cup
14 4 garlic cloves, minced
15 Half a cup unsalted butter

Steps to Follow

Step 01

Flip the oven on to 375 F (190 C) so it’s hot and ready to go.

Step 02

Drop some garlic butter sauce at the bottom of your baking dish, then set down a layer of noodles. Next, dollop more sauce, then shrimp, sprinkle on mozzarella, and just keep repeating. When all your goodies are stacked, finish off with extra sauce and mozzarella right on top.

Step 03

Cover the pan with foil and let it cook for 25 minutes first. After that, peel off the foil and bake it 10 more minutes so the cheese gets a golden top and bubbles up.

Step 04

Once it’s out of the oven, let it sit a bit so it’s easier to slice. Toss on some parsley to make it pop and serve.

Step 05

Boil water with a good bit of salt, toss in lasagna noodles, and cook till they’re flexible. Drain the noodles and leave them off to the side for now.

Step 06

In a big skillet, toss in half a stick of butter on medium heat and melt it. Add in the garlic and let it cook till you can smell it, about a minute or so. Toss in your shrimp and cook both sides till they’re pink and done, then get them out and set aside.

Step 07

Still in your skillet, melt the other half-stick of butter, drop in more garlic, and cook till it starts smelling great. Should only take a minute or two.

Step 08

Sprinkle in all the flour and stir like mad for a minute. You want it all mixed up with no dry spots left.

Step 09

Pour milk in slowly, whisking lots so it stays smooth. Keep cooking and stirring till it thickens up. Pull it off the heat and stir in parmesan so it’s all melted, then salt and pepper it to taste.

Additional Tips

  1. You can use the no-boil lasagna noodles instead and just layer them right in—skip the boiling.
  2. If you like some heat, tossing in a pinch of red pepper to your garlic butter will give it a little zing.
  3. Taste the sauce as you go, and adjust how salty or cheesy you want things.

Essential Tools

  • Aluminum foil
  • Baking dish
  • Whisk
  • Large skillet
  • Big pot

Allergen Information

Always verify ingredient labels for allergens and consult with a healthcare expert if unsure.
  • There’s shellfish (shrimp) and lots of dairy in this.
  • This one’s got wheat, too.

Nutrition Info (Per Serving)

These details are best used as an estimate and shouldn't replace professional health advice.
  • Calories: 495
  • Fat Content: 25 g
  • Carbohydrates: 38 g
  • Protein: 30 g