Irresistible Meat Lovers Pizza Bread

As seen in Satisfying Entrées for Every Table.

Bite into a crusty loaf bursting with gooey mozzarella, provolone, ground beef, and spicy pepperoni, all wrapped up in pillowy dough with a buttery, cheesy topping. It’s easy—brown up beef with spices first, then stretch out your dough, pile on your sauce and cheese, braid the dough over, and bake until it’s all golden on top. Cut thick slices while it’s hot and dunk in extra sauce. It’s a surefire party hit with those bold Italian flavors and cheesy goo, making it perfect for snacking with friends or at a fun family get-together.

Barbara Chef
Created By Sasha
Last updated on Wed, 30 Jul 2025 14:42:10 GMT
A loaded pizza topped with cheese and pepperoni. Save Pin
A loaded pizza topped with cheese and pepperoni. | foodthingle.com

This bubbly pizza bread is packed with juicy beef, pepperoni, layers of gooey cheese, and a rich sauce, all snuggled in tender, fluffy dough. I whip it up for family hangouts and sports nights, and there’s never a crumb left — everyone keeps reaching for another piece.

The first time I gave this a go, my family crowded the oven waiting for it to finish. Now, when Sunday football’s on, it’s a must-make every week.

Tasty Ingredients

  • Pepperoni: adds a big pop of flavor and gets deliciously crispy. Thin rounds keep each bite balanced
  • Provolone cheese: melts creamy and smooth for that mellow cheese pull. Sliced works well for stacking
  • Pizza sauce: keeps everything moist and tangy. Go with a nice thick sauce to dodge soggy bread
  • Butter: smeared on top for that glossy, golden surface
  • Garlic powder: brings a gentle punch without overpowering everything else
  • Grated Parmesan cheese: gives a savory nutty touch to the outside. Freshly grated is best for melting in
  • Shredded mozzarella cheese: creates perfect stretchy-gooey moments. Shred it yourself if you can
  • Kosher salt: bumps up every flavor here
  • Dried oregano: brings homey, classic Italian vibes. A newer bottle really makes a difference
  • Refrigerated pizza dough: the fast track to soft, pillowy bread. Check for a batch that feels elastic
  • Lean ground beef: keeps the insides juicy without a greasy mess. Lower fat is better here

Simple Step Guide

Slice and Enjoy:
Cut your finished loaf into chunky strips, perfect for grabbing. Warm up any leftover sauce if you want something to dip in
Bake it Up:
Slide the bread into the hot oven. Twenty to twenty-five minutes and you’ll have a golden crust with bubbling cheese and amazing smells
Top it Off:
Brush melted butter all over the dough braid then finish with a sprinkle of parmesan and an extra bit of oregano for flavor
Braid the Loaf:
Snip the dough into strips on both long sides, leaving the center packed with filling. Fold strips over the center, one from each side, making a braid or crisscross to seal it all in
Pack in the Goodies:
Plop half a cup of pizza sauce down the middle. Lay out provolone, cover with pepperoni, spread the beef, then pile on mozzarella so every bit is loaded
Roll Out the Dough:
Open your dough onto a baking sheet with raised edges. Smooth out bubbles and keep it all even so it bakes up nice
Add the Sauce:
Once the beef cools a few, pour in a third-cup of pizza sauce and mix it well so the flavor gets everywhere
Brown Up Beef:
In a non-stick pan over medium, break up beef and stir with salt, oregano, and garlic powder. Keep stiring so it’s all cooked through, then drain off extra fat so nothing gets soggy
A pizza with pepperoni and cheese. Save Pin
A pizza with pepperoni and cheese. | foodthingle.com

Good to Remember

  • Feeds about a dozen people—so bring it to parties
  • Cook the beef ahead if you want, it holds up fine in the fridge overnight
  • Wrap up leftovers tight and freeze for later, it keeps well

What really makes this for me? That crispy, golden parmesan crust straight from the oven. One time my brother and I loaded it with so much pepperoni we almost couldn’t close the dough—but every bite was pure, cheesy fun!

Keep It Fresh

If you’ve got leftovers, stash them in a tight container in the fridge up to three days. Warm them slowly in a low oven to keep that crust crisp. Freezing? Wrap in foil, stash for a month, and split into smaller chunks for easy reheats if you want a quick snack later

Swap Ideas

  • Ground turkey or chicken instead of beef makes it a bit lighter
  • Ham or even cooked sausage works fine in place of pepperoni
  • Try any cheese mix—cheddar or fontina are tasty for something different
  • Go with whole wheat or thin dough if you want, but don’t forget that thin ones cook up quicker

How to Serve

Cut into big pieces so folks can just grab and eat—it’s a breeze for casual get togethers. Put out a big bowl of salad or sliced veggies for a fresh boost. If you’re in the mood, put out cups of warm sauce for dipping or drizzle everything with spicy honey for a special kick

A slice of pizza on a wooden table. Save Pin
A slice of pizza on a wooden table. | foodthingle.com

Where It Comes From

This kind of pizza bread borrows from classic Italian stuffed breads like calzones and stromboli. Back then, folks would use leftover meats and cheese all wrapped in dough to make something filling. American cooks updated it, tossing in familiar pizza flavors and store-bought dough, so now it’s super easy to throw together and big on comfort

Common Recipe Questions

→ Which kind of beef should I toss in for this pizza bread?

Go with lean ground beef so you get all the tasty goodness without lots of grease. This way, your bread stays nice and crisp instead of soggy.

→ How do I keep my dough from turning too soft while baking?

Make sure you drain any juice off the beef before using it, and don’t go wild with the sauce or filling—that helps keep things light and not mushy.

→ Are there any other cheeses I can use besides provolone and mozzarella?

For sure! Cheddar, Monterey Jack, or any cheese that turns melty and works with Italian flavors will do just fine.

→ Can I get this bread ready in advance?

Yes, you can put it all together ahead of time and keep it chilling in the fridge. Pop it in the oven right before serving so it comes out fresh and soft.

→ What kinds of sides would go well with pizza bread?

Warm up some extra pizza sauce for dipping—it’s classic! Or throw together a quick salad or serve with an antipasto spread to round things out.

→ Is it okay to try other meats or throw in some veggies?

Absolutely! Add cooked sausage, crispy bacon, or toss in bell peppers and mushrooms you’ve sautéed for a new spin.

Pizza Bread Meat Lovers

Cheesy stuffed loaf with beef and pepperoni, perfect for chill get-togethers and easy party sharing.

Preparation Time
10 Minutes
Cooking Time
30 Minutes
Overall Time
40 Minutes
Created By: Sasha

Recipe Type: Main Dishes

Skill Level: Moderate

Regional Style: Italian

Output: 12 Number of Servings

Special Diets: ~

What You'll Need

→ Main Ingredients

01 2 tablespoons grated Parmesan cheese
02 2 ounces thin-sliced pepperoni (about 1/3 cup)
03 1 cup shredded mozzarella cheese
04 4 slices provolone cheese
05 1 tube (13.8 ounces) refrigerated pizza dough
06 1/2 teaspoon dried oregano, divided
07 2 tablespoons butter, melted
08 1/4 teaspoon garlic powder
09 1 jar pizza sauce, divided
10 1/2 pound lean ground beef
11 1/4 teaspoon kosher salt

Steps to Follow

Step 01

Get the pizza sauce left over nice and hot, then put it out for dunking your pizza bread.

Step 02

Pop it into your hot oven. Let it bake about 20 to 25 minutes, until the top turns a deep golden color and the dough's cooked.

Step 03

Now, brush melted butter on the outside and shower on some grated Parmesan and the remaining dried oregano.

Step 04

Cut both long sides of the dough into strips. Fold them across the filling, criss-crossing to wrap everything up.

Step 05

Put 1/2 cup pizza sauce in the middle of your dough. Top with provolone, a pile of pepperoni, the beef mix, and then mozzarella cheese.

Step 06

Unroll that chilled pizza dough and lay it flat on a rimmed baking sheet.

Step 07

Let the beef cool a bit, then stir in about a third of your pizza sauce.

Step 08

Toss the ground beef in a big skillet with oregano, garlic powder, and salt. Cook over medium heat, stirring now and then, until it’s not pink. Dump out any grease.

Step 09

Crank your oven to 400°F (205°C) first thing so it’s hot when you’re ready.

Additional Tips

  1. Serve it nice and warm, and don’t forget extra sauce for dunking.

Essential Tools

  • Big non-stick skillet
  • Rimmed baking sheet
  • Sharp knife
  • Pastry brush

Allergen Information

Always verify ingredient labels for allergens and consult with a healthcare expert if unsure.
  • Has wheat and milk, might have soy too.

Nutrition Info (Per Serving)

These details are best used as an estimate and shouldn't replace professional health advice.
  • Calories: 310
  • Fat Content: 16 g
  • Carbohydrates: 29 g
  • Protein: 15 g